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Pro-inflammatory cytokines i.e., TNF- and IL-1 may activate the serotoninergic transporter (SERT) via the stimulation of the p38 MAPK pathway, increasing the concentration of other catecholamines in specific brain regions such as the anterior hypothalamus (Zhu et al

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Proteomic analyses further suggest that gene expression changes related to oxidative stress (GPX1, superoxide dismutase 1), metabolism (ACACA, GAPDH), placentation (PGF, VEGF-A), and stem cell differentiation (POU5F1, SOX2) may underlie the observed improvement in embryo quality (Marinaro et al., 2018